Title : Induction by glucose of genes coding for glycolytic enzymes in a pancreatic beta-cell line (INS-1).

Pub. Date : 1997 Jan 31

PMID : 9006960






6 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Glucose (from 5 to 25 mM) induced phosphofructokinase-1 (PFK-1) isoform C, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (4-fold), and L-pyruvate kinase (L-PK) (7-fold) mRNAs. Glucose glyceraldehyde-3-phosphate dehydrogenase Homo sapiens
2 Glucose (from 5 to 25 mM) induced phosphofructokinase-1 (PFK-1) isoform C, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (4-fold), and L-pyruvate kinase (L-PK) (7-fold) mRNAs. Glucose glyceraldehyde-3-phosphate dehydrogenase Homo sapiens
3 Following a 3-day exposure to elevated glucose, a similar induction was observed at the protein level for PFK-1 (isoforms C, M, and L), GAPDH, and L-PK, whereas M-PK expression only increased slightly. Glucose glyceraldehyde-3-phosphate dehydrogenase Homo sapiens
4 The study of the mechanism of GAPDH induction indicated that glucose increased the transcriptional rate of the GAPDH gene but that both transcriptional and post transcriptional effects contributed to GAPDH mRNA accumulation. Glucose glyceraldehyde-3-phosphate dehydrogenase Homo sapiens
5 The study of the mechanism of GAPDH induction indicated that glucose increased the transcriptional rate of the GAPDH gene but that both transcriptional and post transcriptional effects contributed to GAPDH mRNA accumulation. Glucose glyceraldehyde-3-phosphate dehydrogenase Homo sapiens
6 The study of the mechanism of GAPDH induction indicated that glucose increased the transcriptional rate of the GAPDH gene but that both transcriptional and post transcriptional effects contributed to GAPDH mRNA accumulation. Glucose glyceraldehyde-3-phosphate dehydrogenase Homo sapiens