Title : 11beta-Hydroxysteroid dehydrogenase in the brain: a novel regulator of glucocorticoid action?

Pub. Date : 1997 Jan

PMID : 9000459






1 Functional Relationships(s)
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1 11beta-HSD-2 is a much higher affinity, NAD-dependent, exclusive 11beta-dehydrogenase (glucocorticoid inactivating enzyme), which, when colocalized with otherwise nonselective mineralocorticoid receptors (MR), ensures selective access for aldosterone in vivo. NAD hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens