Title : Increased expression of Bcl-2 protein in human uterine leiomyoma and its up-regulation by progesterone.

Pub. Date : 1997 Jan

PMID : 8989276






3 Functional Relationships(s)
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1 Increased expression of Bcl-2 protein in human uterine leiomyoma and its up-regulation by progesterone. Progesterone BCL2 apoptosis regulator Homo sapiens
2 In monolayer cultures of uterine leiomyoma cells under a serum-free condition, the addition of progesterone (100 ng/mL) resulted in a striking increase in Bcl-2 protein expression in the cultured leiomyoma cells relative to that in control cultures, whereas the addition of 17 beta-estradiol (10 ng/mL) resulted in a reduction in Bcl-2 protein expression in the cells. Progesterone BCL2 apoptosis regulator Homo sapiens
3 In monolayer cultures of uterine leiomyoma cells under a serum-free condition, the addition of progesterone (100 ng/mL) resulted in a striking increase in Bcl-2 protein expression in the cultured leiomyoma cells relative to that in control cultures, whereas the addition of 17 beta-estradiol (10 ng/mL) resulted in a reduction in Bcl-2 protein expression in the cells. Progesterone BCL2 apoptosis regulator Homo sapiens