Title : Mechanism of selective incorporation of the melanoma seeker 2-thiouracil into growing melanin.

Pub. Date : 1996 Dec 20

PMID : 8978847






1 Functional Relationships(s)
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1 When incubated with DOPA in the presence of tyrosinase, TU profoundly modified the normal course of melanogenesis, favoring formation of a complex mixture of addition products consisting mainly of 6-S-thiouracil-DOPA as well as DHI-TU adducts. Dihydroxyphenylalanine tyrosinase Mus musculus