Title : The presence of insulin-degrading enzyme in human ileal and colonic mucosal cells.

Pub. Date : 1996 Nov

PMID : 8961169






1 Functional Relationships(s)
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1 In both colon and ileum, cytosolic insulin-degrading activities had a pH optimum at pH 7.5, and were extensively inhibited by each of N-ethylmaleimide, p-chloromercuribenzoate, and 1,10-phenanthroline, but were very weakly affected by each of leupeptin, chymostatin, diisopropyl phosphofluoridate and soybean trypsin inhibitor. p-chloromercuribenzoate insulin Homo sapiens