Title : Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily.

Pub. Date : 1996 Nov

PMID : 8948091






1 Functional Relationships(s)
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1 Our results suggest that in the human liver, the metabolism of diazepam to nordiazepam is mediated by CYP3A4, which has been reported as the most abundant P450 form in human liver as well as 2C19, which has been reported as a polymorphic enzyme. Diazepam cytochrome P450 family 3 subfamily A member 4 Homo sapiens