Title : Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation.

Pub. Date : 1996 Dec

PMID : 8943348






1 Functional Relationships(s)
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1 In addition, mutating Y720 to phenylalanine dramatically reduced PDGF-dependent tyrosine phosphorylation of SHP-2. Phenylalanine protein tyrosine phosphatase non-receptor type 11 Homo sapiens