Title : Metabolic interactions of the proton-pump inhibitors lansoprazole, omeprazole and pantoprazole with other drugs.

Pub. Date : 1996 Oct

PMID : 8930576






1 Functional Relationships(s)
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1 The substrates and inhibitors of CYP2C19 and CYP3A4 and the known genetic polymorphism of CYP2C19 explain some but not all of the interactions of lansoprazole, and particularly the interactions of omeprazole with carbamazepine, diazepam, phenytoin and theophylline or caffeine. Diazepam cytochrome P450 family 3 subfamily A member 4 Homo sapiens