Pub. Date : 1996 May
PMID : 8928831
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the presence of AVP and hyperosmolality (75 mM NaCl added to perfusate and bath), PGE2 increased JHCO3 from 1.4 +/- 0.1 to 7.5 +/- 0.5 pmol.min-1.mm-1 (P < 0.005). | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 2 | PGE2 also stimulated JHCO3 in the presence of AVP and hypertonic urea. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 3 | The stimulation of JHCO3 by PGE2 in the presence of AVP was blocked by pretreatment with pertusis toxin (PTX, 2 x 10(-11) or 10(-8) M). | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 4 | PGE2 may act as a counterregulatory factor to maintain a stable rate of HCO3- absorption in the MTAL during antidiuresis when circulating AVP levels and medullary osmolality are elevated. | Dinoprostone | arginine vasopressin | Rattus norvegicus |