Title : Membrane-associated phospholipase D activity in neural cell line PC12.

Pub. Date : 1996 Sep

PMID : 8906568






3 Functional Relationships(s)
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1 Two different types of PLD activity, oleate-dependent and GTP gamma S-dependent, were examined by using exogenous [3H]phosphatidylcholine substrate. Guanosine Triphosphate glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
2 PLD activity of the membrane fraction of PC12 cells was highly dependent on oleate and independent of GTP gamma S. This profile is in sharp contrast to that observed in HL60 cells showing the profound GTP gamma S-induced activation of PLD. Guanosine Triphosphate glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
3 PLD activity of the membrane fraction of PC12 cells was highly dependent on oleate and independent of GTP gamma S. This profile is in sharp contrast to that observed in HL60 cells showing the profound GTP gamma S-induced activation of PLD. Guanosine Triphosphate glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens