Pub. Date : 1996 Oct 11
PMID : 8874536
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To understand the mechanism underlying the neurotoxicity of lithium ion, we investigated the inhibition of the nerve growth factor-induced neuronal differentiation of rat PC12 pheochromocytoma cells induced by treatment with LiCl. | Lithium Chloride | nerve growth factor | Rattus norvegicus |
| 2 | Incubation with 0.1-3 mM LiCl from 30 min before nerve growth factor (NGF) treatment attenuated neurite outgrowth. | Lithium Chloride | nerve growth factor | Rattus norvegicus |
| 3 | Incubation with 0.1-3 mM LiCl from 30 min before nerve growth factor (NGF) treatment attenuated neurite outgrowth. | Lithium Chloride | nerve growth factor | Rattus norvegicus |
| 4 | These observations, that chronic treatment with LiCl inhibits the NGF-induced neuronal differentiation in a transcription-dependent manner and inhibits phosphoinositide metabolism, suggest a possible causal relationship between these two events. | Lithium Chloride | nerve growth factor | Rattus norvegicus |