Pub. Date : 1996 Jan
PMID : 8839355
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DHT treatment in combination with estradiol further decreased estrogen receptor content in the BNST, ARC and VMN, relative to the estradiol-only animals. | Dihydrotestosterone | estrogen receptor 1 | Rattus norvegicus |
| 2 | In animals in which the DHT capsules were removed after 4 days of exposure, allowing the estradiol to remain for a further 4 days, estrogen receptor levels were indistinguishable from those measured in control animals treated for 8 days with estradiol alone. | Dihydrotestosterone | estrogen receptor 1 | Rattus norvegicus |
| 3 | These results demonstrate that sustained estrogen exposure downregulates levels of estrogen receptor in the brain and confirm that DHT synergizes with estrogen in inducing this response in some, but not all, target neuronal groups. | Dihydrotestosterone | estrogen receptor 1 | Rattus norvegicus |