Title : Protamine enhances the activity of human recombinant interferon-gamma.

Pub. Date : 1996 Jul

PMID : 8836919






3 Functional Relationships(s)
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1 We have shown recently that IFN-gamma-mediated effects can be blocked by heparin and that this inhibitory effect can be abrogated by the addition of protamine. Heparin interferon gamma Homo sapiens
2 In this report, we show that the antagonistic effect of protamine on heparin-mediated inhibition of IFN-gamma activity is mainly due to the capacity of protamine to enhance IFN-gamma activity. Heparin interferon gamma Homo sapiens
3 In this report, we show that the antagonistic effect of protamine on heparin-mediated inhibition of IFN-gamma activity is mainly due to the capacity of protamine to enhance IFN-gamma activity. Heparin interferon gamma Homo sapiens