Title : Effect of interferon on 5-fluorouracil-induced perturbations in pools of deoxynucleotide triphosphates and DNA strand breaks.

Pub. Date : 1996

PMID : 8823494






1 Functional Relationships(s)
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Protein Name
Organism
1 Interferon (IFN) augments the anabolism of 5-fluorouracil (5FU) to its active metabolite, fluorodeoxyuridylate (FdUMP), which inhibits thymidylate synthase (TS). Fluorodeoxyuridylate thymidylate synthetase Homo sapiens