Title : Effect of pulmonary surfactant protein A and neutral lipid on accretion and organization of dipalmitoylphosphatidylcholine in surface films.

Pub. Date : 1996 Jun

PMID : 8808762






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SP-A enhanced the rate of lipid adsorption, while both SP-A and NL increased the extent of DPPC accumulation. 1,2-Dipalmitoylphosphatidylcholine pulmonary surfactant-associated protein A Bos taurus
2 Addition of SP-A to lipid extracts without NL generated DPPC aggregates; more uniform larger aggregates appeared in the presence of SP-A and NL. 1,2-Dipalmitoylphosphatidylcholine pulmonary surfactant-associated protein A Bos taurus
3 These results indicate that neutral lipid cooperates with surfactant-associated protein A to organize dipalmitoylphosphatidylcholine in the surface films and enhance formation of a DPPC-rich reservoir below the air-water interface. 1,2-Dipalmitoylphosphatidylcholine pulmonary surfactant-associated protein A Bos taurus
4 These results indicate that neutral lipid cooperates with surfactant-associated protein A to organize dipalmitoylphosphatidylcholine in the surface films and enhance formation of a DPPC-rich reservoir below the air-water interface. 1,2-Dipalmitoylphosphatidylcholine pulmonary surfactant-associated protein A Bos taurus