Pub. Date : 1996 Jun
PMID : 8800366
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of C-peptide administration on whole body glucose utilization in STZ-induced diabetic rats. | Glucose | insulin 2 | Rattus norvegicus |
| 2 | Recent studies suggest that C-peptide stimulates glucose transport in isolated skeletal muscle. | Glucose | insulin 2 | Rattus norvegicus |
| 3 | The metabolic clearance rate of glucose (MCR) for the diabetic rats receiving C-peptide (12.0 +/- 1.0 mL kg-1 min-1) was significantly (P < 0.01) higher than that in the diabetic rats given saline (6.3 +/- 0.7 mL kg-1 min-1) or a randomly scrambled C-peptide (7.8 +/- 1.3 mL kg-1 min-1) at low-dose insulin infusion but not at the high-dose insulin infusion. | Glucose | insulin 2 | Rattus norvegicus |
| 4 | The metabolic clearance rate of glucose (MCR) for the diabetic rats receiving C-peptide (12.0 +/- 1.0 mL kg-1 min-1) was significantly (P < 0.01) higher than that in the diabetic rats given saline (6.3 +/- 0.7 mL kg-1 min-1) or a randomly scrambled C-peptide (7.8 +/- 1.3 mL kg-1 min-1) at low-dose insulin infusion but not at the high-dose insulin infusion. | Glucose | insulin 2 | Rattus norvegicus |
| 5 | These results thus demonstrate that C-peptide has the capacity to increase glucose utilization in STZ-induced diabetic rats. | Glucose | insulin 2 | Rattus norvegicus |