Title : Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation.

Pub. Date : 1996 Jun

PMID : 8799551






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 iNOS mRNA was detected between 3 to 10 h following carrageenan administration using ribonuclease protection assays. Carrageenan nitric oxide synthase 2 Rattus norvegicus
2 iNOS protein was first detected 6 h and was maximal 10 h following carrageenan administration as shown by Western blot analysis. Carrageenan nitric oxide synthase 2 Rattus norvegicus
3 Administration of the iNOS inhibitors 5 h after carrageenan (a time point where iNOS was expressed) inhibited paw oedema at all subsequent time points. Carrageenan nitric oxide synthase 2 Rattus norvegicus