Pub. Date : 1996 May 13
PMID : 8782901
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Incubation of rat microglial cells with A beta(1-40) caused a significant increase in nitrite, a stable metabolite of nitric oxide (NO), in culture media, while there was no detectable increase in nitrite in astrocyte-rich glial cells or cortical neurons after incubation with A beta(1-40). | Nitrites | amyloid beta precursor protein | Homo sapiens |
| 2 | Nitrite production by microglial cells was also induced by A beta(1-42), but not A beta(25-35). | Nitrites | amyloid beta precursor protein | Homo sapiens |
| 3 | Among the various cytokines investigated such as interleukin-1, interleukin-6, tumor necrosis factor-alpha and interferon-gamma (IFN-gamma), only IFN-gamma markedly enhanced A beta-dependent nitrite production. | Nitrites | amyloid beta precursor protein | Homo sapiens |