Pub. Date : 1996 Aug
PMID : 8765045
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The results reported here indicate that the resting, nonphosphorylated BCR associates with the Grb-2/Sos-linker SHC via the Ig-alpha immunoreceptor-based tyrosine activation motif (ITAM). | Tyrosine | xylosyltransferase 2 | Homo sapiens |
2 | In view of previous studies which demonstrated p21ras co-capping with ligated BCR, the data presented here suggest that Ig-alpha/beta- and SHC tyrosine phosphorylation-dependent recruitment of the Grb2/Sos complex to the receptor can occur and may provide a mechanism by which the nucleotide exchange activity of Sos could mediate activation of BCR-localized p21ras. | Tyrosine | xylosyltransferase 2 | Homo sapiens |
3 | In view of previous studies which demonstrated p21ras co-capping with ligated BCR, the data presented here suggest that Ig-alpha/beta- and SHC tyrosine phosphorylation-dependent recruitment of the Grb2/Sos complex to the receptor can occur and may provide a mechanism by which the nucleotide exchange activity of Sos could mediate activation of BCR-localized p21ras. | Tyrosine | xylosyltransferase 2 | Homo sapiens |