Title : Abnormal glutathione and sulfate levels after interleukin 6 treatment and in tumor-induced cachexia.

Pub. Date : 1996 Aug

PMID : 8751725






1 Functional Relationships(s)
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1 IL-6 treatment or inoculation of the MCA-105 fibrosarcoma caused a significant increase in hepatic gamma-glutamyl-cysteine synthetase activity and a decrease in the sulfate level, glutamine/urea ratio, and glutamine/glutamate ratio, suggesting that a decrease of the proton generating cysteine catabolism in the liver may increase carbamoyl-phosphate synthesis and urea formation at the expense of net glutamine synthesis. Carbamyl Phosphate interleukin 6 Mus musculus