Title : Caffeine-induced expression of c-fos mRNA and NGFI-A mRNA in caudate putamen and in nucleus accumbens are differentially affected by the N-methyl-D-aspartate receptor antagonist MK-801.

Pub. Date : 1996 Jan

PMID : 8717354






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Caffeine-induced expression of c-fos mRNA and NGFI-A mRNA in caudate putamen and in nucleus accumbens are differentially affected by the N-methyl-D-aspartate receptor antagonist MK-801. Caffeine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 The two NMDA receptor antagonists significantly reduced the caffeine-induced expression of both c-fos mRNA and NGFI-A mRNA in the medial part of the caudate putamen. Caffeine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
3 These findings suggest that glutamatergic transmission via NMDA receptors contributes to the induction of c-fos mRNA and NGFI-A mRNA by caffeine in striatum. Caffeine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus