Title : Proinflammatory agents, IL-8 and IL-10, upregulate inducible nitric oxide synthase expression and nitric oxide production in avian osteoclast-like cells.

Pub. Date : 1996 Mar 15

PMID : 8707887






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 inhibitors of NOS activity (aminoguanidine, L-NAME) or iNOS induction (dexamethasone, TGF beta) reduced LPS-stimulated nitrite production. Nitrites nitric oxide synthase 2 Homo sapiens
2 Induction of iNOS mRNA by LPS, or by proinflammatory cytokines, occurred prior to the rise of medium nitrite in time course studies and was diminished by dexamethasone. Nitrites nitric oxide synthase 2 Homo sapiens