Pub. Date : 1996 Aug 30
PMID : 8702933
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Palmitoylated cysteine 341 modulates phosphorylation of the beta2-adrenergic receptor by the cAMP-dependent protein kinase. | Cysteine | adrenoceptor beta 2 | Homo sapiens |
| 2 | We previously showed that substitution of a glycine residue for the palmitoylated cysteine 341 of the human beta2-adrenergic receptor (Gly341beta2AR), increases the basal level of the receptor phosphorylation and reduces its ability to functionally interact with Gs. | Cysteine | adrenoceptor beta 2 | Homo sapiens |
| 3 | Taken together, the data demonstrate that palmitoylation of cysteine 341 controls the phosphorylation state of the PKA site located in the carboxyl tail of the beta2AR and by doing so modulates the responsiveness of the receptor. | Cysteine | adrenoceptor beta 2 | Homo sapiens |