Title : Molecular cloning of the rat inducible nitric oxide synthase gene promoter.

Pub. Date : 1996 Jun 25

PMID : 8687469






2 Functional Relationships(s)
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1 Previously, we have reported the most interesting feature of rat iNOS gene that is up-regulated by cyclic AMP at transcriptional level as demonstrated by nuclear run-on assay. Cyclic AMP nitric oxide synthase 2 Rattus norvegicus
2 Moreover, we have constructed a rat iNOS promoter-chloramphenicol acetyltransferase (CAT) fusion gene and analyzed its inducibility by interleukin 1 beta and cyclic AMP in transiently transfected Swiss 3T3 fibroblasts. Cyclic AMP nitric oxide synthase 2 Rattus norvegicus