Pub. Date : 1996 Jun
PMID : 8682650
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Heparan sulfate-dependent and low density lipoprotein receptor-related protein-dependent catabolic pathways for lipoprotein lipase in mouse embryonic fibroblasts. | Heparitin Sulfate | lipoprotein lipase | Mus musculus |
| 2 | Heparan sulfate and low density lipoprotein receptor related protein (LRP) have been shown to participate in the uptake and degradation of the enzyme lipoprotein lipase (LPL). | Heparitin Sulfate | lipoprotein lipase | Mus musculus |
| 3 | Heparan sulfate and low density lipoprotein receptor related protein (LRP) have been shown to participate in the uptake and degradation of the enzyme lipoprotein lipase (LPL). | Heparitin Sulfate | lipoprotein lipase | Mus musculus |
| 4 | Assuming that a) heparinase treatment abolished the heparan-sulfate pathway, and that b) the degradation remaining in heparin-treated cultures represents nonspecific values, it appears that heparan sulfate contributes about 61%, 83% and 95% of total LPL degradation, whereas the LRP pathway contributes 39%, 17% and less than 5% of LPL degradation in MEF, PEA-10 and PEA-13 cells, respectively. | Heparitin Sulfate | lipoprotein lipase | Mus musculus |
| 5 | Assuming that a) heparinase treatment abolished the heparan-sulfate pathway, and that b) the degradation remaining in heparin-treated cultures represents nonspecific values, it appears that heparan sulfate contributes about 61%, 83% and 95% of total LPL degradation, whereas the LRP pathway contributes 39%, 17% and less than 5% of LPL degradation in MEF, PEA-10 and PEA-13 cells, respectively. | Heparitin Sulfate | lipoprotein lipase | Mus musculus |
| 6 | In addition, the data indicate that LPL interaction with heparan sulfate and the LRP pathways is independent of each other. | Heparitin Sulfate | lipoprotein lipase | Mus musculus |