Title : Bcl-2 inhibits hydrogen peroxide-induced ER Ca2+ pool depletion.

Pub. Date : 1996 May 16

PMID : 8668330






1 Functional Relationships(s)
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1 H2O2 treatment produced a significant reduction in the TG-mobilizable Ca2+ pool in WEH17.2 and W.Hb13 cells, but not in W.Hb12 cells, indicating that overexpression of Bcl-2 preserves the integrity of the ER Ca2+ pool in cells exposed to reactive oxygen species. Thapsigargin BCL2 apoptosis regulator Homo sapiens