Pub. Date : 1996 Jul 26
PMID : 8663494
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, in the case of receptors containing alpha3 and beta2 subunits, the addition of alpha5 subunits reduced the EC50 for acetylcholine from 28 to 0.5 microM and the EC50 for nicotine from 6.8 to 1.9 microM, while increasing the efficacy of nicotine from 50% on alpha3beta2 receptors to 100% on alpha3beta2alpha5 receptors. | Nicotine | potassium calcium-activated channel subfamily M regulatory beta subunit 2 | Homo sapiens |
| 2 | However, in the case of receptors containing alpha3 and beta2 subunits, the addition of alpha5 subunits reduced the EC50 for acetylcholine from 28 to 0.5 microM and the EC50 for nicotine from 6.8 to 1.9 microM, while increasing the efficacy of nicotine from 50% on alpha3beta2 receptors to 100% on alpha3beta2alpha5 receptors. | Nicotine | potassium calcium-activated channel subfamily M regulatory beta subunit 2 | Homo sapiens |