PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8663494-9 1996 However, in the case of receptors containing alpha3 and beta2 subunits, the addition of alpha5 subunits reduced the EC50 for acetylcholine from 28 to 0.5 microM and the EC50 for nicotine from 6.8 to 1.9 microM, while increasing the efficacy of nicotine from 50% on alpha3beta2 receptors to 100% on alpha3beta2alpha5 receptors. Nicotine 178-186 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 56-61 8663494-9 1996 However, in the case of receptors containing alpha3 and beta2 subunits, the addition of alpha5 subunits reduced the EC50 for acetylcholine from 28 to 0.5 microM and the EC50 for nicotine from 6.8 to 1.9 microM, while increasing the efficacy of nicotine from 50% on alpha3beta2 receptors to 100% on alpha3beta2alpha5 receptors. Nicotine 244-252 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 56-61