Title : Inhibition of alpha interferon but not gamma interferon signal transduction by phorbol esters is mediated by a tyrosine phosphatase.

Pub. Date : 1996 Apr

PMID : 8657115






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Phorbol ester treatment of monocytes inhibited IFN alpha-stimulated tyrosine phosphorylation of the transcription factors Stat1alpha, Stat2, and Stat3 and of the tyrosine kinase Tyk2 but had no effect on IFN-gamma activation of Stat1alpha. Tyrosine signal transducer and activator of transcription 2 Homo sapiens