Title : Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver.

Pub. Date : 1996 Apr 15

PMID : 8645011






1 Functional Relationships(s)
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1 A recent report, in which cultured tumor cells were used, identified farnesol as the nonsterol mevalonate-derived metabolite required for the accelerated degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (C. C. Correll, L. Ng, and P. A. Edwards, 1994, J. Biol. Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus