Title : Inactivation of gamma-aminobutyric acid aminotransferase by L-3-chloroalanine hydroxamate.

Pub. Date : 1995 Jan

PMID : 8612042






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Inactivation of [3H]PLP-reconstituted GABA-AT with 1 followed by denaturation gave no PMP or enamine adduct to the PLP; however, a new unknown metabolite was observed which was identical to the metabolite formed upon inactivation of GABA-AT by L-cycloserine. L-Cycloserine 4-aminobutyrate aminotransferase Homo sapiens
2 L-3-Chloroalanine hydroxamate was shown to undergo buffer-catalyzed cyclization to L-cycloserine, which is the actual inactivator of GABA-AT. L-Cycloserine 4-aminobutyrate aminotransferase Homo sapiens