Title : Bis-intercalation of a homodimeric thiazole orange dye in DNA in symmetrical pyrimidine-pyrimidine-purine-purine oligonucleotides.

Pub. Date : 1996 Mar 1

PMID : 8600453






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The complexes of TOTO with d(CGCTAGCGCTAGCG)2 (10) and d(CGCTAGCCGGCG):d(CGCCGGCTAGCG) (11) oligonucleotides, each containing two preferential binding sites, was also examined. Oligonucleotides HOP homeobox Homo sapiens
2 In both cases TOTO forms mixtures of 1:1 and 1:2 dsDNA-TOTO complexes in ratios dependent on the relative amount of TOTO and the oligonucleotides in the sample. Oligonucleotides HOP homeobox Homo sapiens
3 In both cases TOTO forms mixtures of 1:1 and 1:2 dsDNA-TOTO complexes in ratios dependent on the relative amount of TOTO and the oligonucleotides in the sample. Oligonucleotides HOP homeobox Homo sapiens
4 Binding of TOTO to the two oligonucleotides is sequence selective at the (5"-CTAG-3")2 and (5"-CCGG-3")2 sites. Oligonucleotides HOP homeobox Homo sapiens