Protein Name HOP homeobox
Organism Homo sapiens
Gene ID 84525
Gene Symbol

HOPX

UniProt Q9BPY8 (HOP_HUMAN)
Relationships Total Number of functionally related compound(s) : 103
Total Number of Articles : 83
Description

HOP homeobox

Gene Summary

The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2009]

synonyms
  • homeodomain-only protein
  • lung cancer-associated Y protein
  • not expressed in choriocarcinoma clone 1
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Properties