Title : Growth hormone secretion in human acromegalic pituitary adenomas: cyclic adenosine monophosphate and protein kinase C responses.

Pub. Date : 1996 Feb

PMID : 8596491






1 Functional Relationships(s)
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1 These results suggest that TPA, an activator of PKC, has a stimulatory effect on GRH-induced cAMP production and that, finally, TRH- and CRH-induced PKC activation may cause greater secretion of GH by enhancement of cAMP production in human GH-hypersecreting adenoma cells. Tetradecanoylphorbol Acetate gonadotropin releasing hormone 1 Homo sapiens