Title : Influence of oestradiol-17 beta on interleukin-1 secretion by endotoxin-stimulated porcine mononuclear cells in vitro.

Pub. Date : 1995 Jul

PMID : 8592902






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1 Influence of oestradiol-17 beta on interleukin-1 secretion by endotoxin-stimulated porcine mononuclear cells in vitro. Estradiol interleukin 1 alpha Homo sapiens
2 By use of this bioassay, the influence of increasing concentrations of oestradiol-17 beta on IL-1 secretion by endotoxin-stimulated porcine mononuclear cells (MNC) in vitro was studied. Estradiol interleukin 1 alpha Homo sapiens
3 The IL-1 secretion by the MNC, as determined by the D-10 bioassay, was significantly (P < 0.01) suppressed by the highest oestradiol concentration tested (1500 pmol/l). Estradiol interleukin 1 alpha Homo sapiens
4 The results indicate that high physiological concentrations of oestradiol-17 beta may affect the secretion of IL-1 by porcine MNC. Estradiol interleukin 1 alpha Homo sapiens