Title : A decrease in angiotensin receptor binding in rat brain nuclei by antisense oligonucleotides to the angiotensin AT1 receptor.

Pub. Date : 1995 Oct 20

PMID : 8584752






1 Functional Relationships(s)
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1 injections of antisense oligonucleotides against mRNA of the angiotensin type 1 (AT1) receptor have been shown to reduce blood pressure in spontaneously hypertensive (SHR) rats and angiotensin II-induced drinking in both SHR and Sprague-Dawley (SD) rats. Oligonucleotides angiotensinogen Rattus norvegicus