Pub. Date : 1995
PMID : 8584678
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the striatum AAAD activity is increased by neuronal firing and diminished or enhanced by activation or blocking dopamine (DA) D1 or D2 receptors, respectively. | Dopamine | dopa decarboxylase | Homo sapiens |
| 2 | In the striatum AAAD activity is increased by neuronal firing and diminished or enhanced by activation or blocking dopamine (DA) D1 or D2 receptors, respectively. | Dopamine | dopa decarboxylase | Homo sapiens |
| 3 | In Parkinson"s disease AAAD is the rate-controlling enzyme for the synthesis of DA when L-DOPA is administered and any change of AAAD activity could have clinical consequences. | Dopamine | dopa decarboxylase | Homo sapiens |
| 4 | In Parkinson"s disease AAAD is the rate-controlling enzyme for the synthesis of DA when L-DOPA is administered and any change of AAAD activity could have clinical consequences. | Dopamine | dopa decarboxylase | Homo sapiens |
| 5 | Indeed, the "on-off phenomenon" where there are fluctuations between off-periods of marked akinesia over several hours with on-periods of improved motility may be related to oscillating or poorly modulated AAAD activity and conversion of L-DOPA to DA. | Dopamine | dopa decarboxylase | Homo sapiens |