PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8584678-2	1995	In the striatum AAAD activity is increased by neuronal firing and diminished or enhanced by activation or blocking dopamine (DA) D1 or D2 receptors, respectively.	Dopamine	115-123	dopa decarboxylase	Homo sapiens	16-20	
8584678-2	1995	In the striatum AAAD activity is increased by neuronal firing and diminished or enhanced by activation or blocking dopamine (DA) D1 or D2 receptors, respectively.	Dopamine	125-127	dopa decarboxylase	Homo sapiens	16-20	
8584678-4	1995	In Parkinson"s disease AAAD is the rate-controlling enzyme for the synthesis of DA when L-DOPA is administered and any change of AAAD activity could have clinical consequences.	Dopamine	80-82	dopa decarboxylase	Homo sapiens	23-27	
8584678-4	1995	In Parkinson"s disease AAAD is the rate-controlling enzyme for the synthesis of DA when L-DOPA is administered and any change of AAAD activity could have clinical consequences.	Dopamine	80-82	dopa decarboxylase	Homo sapiens	129-133	
8584678-5	1995	Indeed, the "on-off phenomenon" where there are fluctuations between off-periods of marked akinesia over several hours with on-periods of improved motility may be related to oscillating or poorly modulated AAAD activity and conversion of L-DOPA to DA.	Dopamine	248-250	dopa decarboxylase	Homo sapiens	206-210