Title : Benzene: a case study in parent chemical and metabolite interactions.

Pub. Date : 1995 Dec 28

PMID : 8571360






1 Functional Relationships(s)
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1 A combination of metabolites (hydroquinone and phenol for example) is apparently necessary to duplicate the hematotoxic effect of benzene, perhaps due in part to the synergistic effect of phenol on myeloperoxidase-mediated oxidation of hydroquinone to the reactive metabolite benzoquinone. quinone myeloperoxidase Homo sapiens