Title : Serine protease inhibitors block priming of monocytes for enhanced release of superoxide.

Pub. Date : 1995 Dec

PMID : 8567031






2 Functional Relationships(s)
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1 The ability of LPS, IFN-gamma, TNF-alpha or PAF to maintain the high superoxide response was blocked by addition of inhibitors of serine proteases, either 4-(2-aminoethyl)-benzenesulphonyl fluoride (AEBSF) or 3,4-dichloroisocoumarin. Superoxides interferon gamma Homo sapiens
2 We conclude that activity of a monocyte serine protease is required to maintain the high superoxide response in monocytes primed with LPS, IFN-gamma, TNF-alpha, or PAF. Superoxides interferon gamma Homo sapiens