Title : Tumor necrosis factor-alpha and interferon-gamma inhibit insulin secretion and cause DNA damage in unweaned-rat islets. Extent of nitric oxide involvement.

Pub. Date : 1996 Feb

PMID : 8549863






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Used alone or in combination, TNF and IFN significantly enhanced the activity of inducible nitric oxide synthase as determined by measuring the conversion of 14C-labeled arginine to 14C-labeled citrulline and nitric oxide. Carbon-14 tumor necrosis factor Rattus norvegicus
2 Used alone or in combination, TNF and IFN significantly enhanced the activity of inducible nitric oxide synthase as determined by measuring the conversion of 14C-labeled arginine to 14C-labeled citrulline and nitric oxide. Carbon-14 tumor necrosis factor Rattus norvegicus