Title : Inhibition of the conversion of pre-interleukins-1 alpha and 1 beta to mature cytokines by p-benzoquinone, a metabolite of benzene.

Pub. Date : 1995 Dec 22

PMID : 8548860






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These findings support our observations in a mouse model that benzene-induced bone marrow cell depression results from a lack of interleukin-1 alpha subsequent to an inhibition by benzoquinone of calpain, the protease required for converting pre-interleukin-1 alpha to active cytokine. quinone interleukin 1 alpha Mus musculus