Title : Molecular genetic analysis of the human sorbitol dehydrogenase gene.

Pub. Date : 1995 Sep

PMID : 8535074






2 Functional Relationships(s)
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1 The polyol pathway comprises the enzymes aldose reductase and sorbitol dehydrogenase, which convert glucose to sorbitol and sorbitol to fructose, respectively, particularly in hyperglycemic states. Sorbitol sorbitol dehydrogenase Homo sapiens
2 Inappropriate sorbitol accumulation in some patients may be the result of polymorphic variation in the human sorbitol dehydrogenase gene, causing reduced expression levels or enzymatic activity. Sorbitol sorbitol dehydrogenase Homo sapiens