Title : Mutation of a phenylalanine conserved in SH3-containing tyrosine kinases activates the transforming ability of c-Abl.

Pub. Date : 1993 Jul

PMID : 8510937






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mutation of a phenylalanine conserved in SH3-containing tyrosine kinases activates the transforming ability of c-Abl. Phenylalanine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 Phenylalanine 420 is perfectly conserved among tyrosine kinases with N-terminal SH3 domains (the Src and Abl families). Phenylalanine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
3 Mutation of phenylalanine 420 to other hydrophobic residues activates c-Abl. Phenylalanine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens