Title : Phosphatidylcholine is a major source of phosphatidic acid and diacylglycerol in angiotensin II-stimulated vascular smooth-muscle cells.

Pub. Date : 1993 Jun 1

PMID : 8503884






5 Functional Relationships(s)
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1 Our experiments suggest that phospholipase D (PLD)-mediated phosphatidylcholine (PtdCho) hydrolysis is the major source of both DG and PtdOH during the late signalling phase. Phosphatidylcholines glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
2 Our experiments suggest that phospholipase D (PLD)-mediated phosphatidylcholine (PtdCho) hydrolysis is the major source of both DG and PtdOH during the late signalling phase. Phosphatidylcholines glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
3 Our experiments suggest that phospholipase D (PLD)-mediated phosphatidylcholine (PtdCho) hydrolysis is the major source of both DG and PtdOH during the late signalling phase. Phosphatidylcholines glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
4 Our experiments suggest that phospholipase D (PLD)-mediated phosphatidylcholine (PtdCho) hydrolysis is the major source of both DG and PtdOH during the late signalling phase. Phosphatidylcholines glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
5 Thus, in angiotensin II-stimulated cultured vascular smooth-muscle cells, PLD-mediated PtdCho hydrolysis is the major source of sustained DG and PtdOH, whereas phosphoinositide breakdown is a minor contributor. Phosphatidylcholines glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens