Title : Identification of an autoinhibitory domain in the insulin receptor tyrosine kinase.

Pub. Date : 1993 Mar 24

PMID : 8487750






1 Functional Relationships(s)
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1 This synthetic peptide gave inhibition of the insulin receptor tyrosine kinase autophosphorylation and phosphorylation of the exogenous substrate poly(Glu, Tyr) with an approximate IC50 of 100 microM. Glutamic Acid ret proto-oncogene Homo sapiens