Pub. Date : 1993 Apr
PMID : 8476723
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Patients with pyridoxine-resistant forms of PH1 usually require organ replacement therapy, i.e. liver transplantation to supply the deficient enzyme and/or kidney transplantation to replace the affected organ. | Pyridoxine | alanine--glyoxylate and serine--pyruvate aminotransferase | Homo sapiens |
| 2 | Isolated liver transplantation should be considered in carefully selected children with severe forms of pyridoxine-resistance (PH1) before GFR has dropped to less than 30 ml/min per 1.73 m2; it seems to be indicated especially in the presence of a rapid decline of GFR in the preceding year. | Pyridoxine | alanine--glyoxylate and serine--pyruvate aminotransferase | Homo sapiens |