Title : Granulocyte-macrophage colony-stimulating factor induces human melanoma-cell migration.

Pub. Date : 1993 Apr 1

PMID : 8473054






2 Functional Relationships(s)
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1 Pre-treatment of cells for 2 hr with non-toxic concentrations of pertussis toxin (PT) or amiloride resulted in a 50% inhibition of chemotaxis to GM-CSF. Amiloride colony stimulating factor 2 Homo sapiens
2 Therefore, GM-CSF, through PT- and amiloride-sensitive signal pathways, is a potent attractant for melanoma cells, the response to which is additive to that of other attractants. Amiloride colony stimulating factor 2 Homo sapiens