Pub. Date : 1993 Mar
PMID : 8435848
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Identification of three genes required for the glucose-dependent transcription of the yeast transcriptional activator ADR1. | Glucose | DNA-binding transcription factor ADR1 | Saccharomyces cerevisiae S288C |
| 2 | Glucose repression of the ADH2 gene from Saccharomyces cerevisiae is mediated by the synthesis and activity of the transcriptional activator ADR1. | Glucose | DNA-binding transcription factor ADR1 | Saccharomyces cerevisiae S288C |
| 3 | In this study, we isolated mutations in three new genes (SAF1, SAF2 and SAF3) that suppressed the glucose-insensitive expression of ADH2 caused by the ADR1-5c allele. | Glucose | DNA-binding transcription factor ADR1 | Saccharomyces cerevisiae S288C |
| 4 | Each of the mutated SAF genes was found to suppress ADR1-5c activity by lowering ADR1-5c steady state mRNA levels 5- to 8-fold under glucose growth conditions. | Glucose | DNA-binding transcription factor ADR1 | Saccharomyces cerevisiae S288C |
| 5 | Each of the mutated SAF genes was found to suppress ADR1-5c activity by lowering ADR1-5c steady state mRNA levels 5- to 8-fold under glucose growth conditions. | Glucose | DNA-binding transcription factor ADR1 | Saccharomyces cerevisiae S288C |
| 6 | The stability of ADR1-5c mRNA was unaffected by mutations in each of the SAF genes, implying that the SAF genes are required for the transcription of ADR1 mRNA under glucose growth conditions. | Glucose | DNA-binding transcription factor ADR1 | Saccharomyces cerevisiae S288C |