Title : Specific glycosaminoglycans support the inhibition of thrombin by plasminogen activator inhibitor 1.

Pub. Date : 1993 Feb 16

PMID : 8431448






2 Functional Relationships(s)
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1 Inhibition of thrombin by PAI-1 was quantitatively analyzed in the presence of a wide range of concentrations of heparin, heparan sulfate, dermatan sulfate, chondroitin 4-sulfate, chondroitin 6-sulfate, keratan sulfate, and hyaluronic acid by measuring residual amidolytic activity. Heparin serpin family E member 1 Homo sapiens
2 Heparin, at concentrations between 0.1 and 1 microgram/mL, significantly promoted thrombin inhibition by PAI-1 as well as SDS-stable complex formation. Heparin serpin family E member 1 Homo sapiens